Mostly inherited as an autosomal dominant entity with variable penetrance and caused by defects that occur in the anterior-posterior patterning of limb development. preaxial polydactyly (radial), central polydactyly (axial), and postaxial polydactyly (ulnar). Broadly, the non-syndromic polydactyly has been classified into three types, i.e. Polydactyly, also known as hyperdactyly or hexadactyly is the most common hereditary limb anomaly characterized by extra fingers or toes, with various associated morphologic phenotypes as part of a syndrome (syndromic polydactyly) or may occur as a separate event (non-syndromic polydactyly).
2Division of Genetics, Department of Pediatrics, King Abdulaziz Medical City, Ministry of National Guard-Health Affairs (NGHA), King Abdullah International Medical Research Centre, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.1Department of Biochemistry, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.Muhammad Umair 1*, Farooq Ahmad 1, Muhammad Bilal 1, Wasim Ahmad 1 and Majid Alfadhel 2
0 kommentar(er)
